Description
Panect DSR is composed of two medicines, namely: Domperidone and Pantoprazole. Domperidone is a prokinetic and anti-nausea agent that helps to treat indigestion and stomach pain. On the other hand, Pantoprazole is a proton pump inhibitor that reduces the excess stomach acid formation by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). Panect DSR is a widely used medicine to treat peptic ulcers and gastroesophageal reflux disease (GERD). Panect DSR prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.
Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and in this way reduces the feeling of bloating, or fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone – CTZ) located in your brain, that is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum.
It should be taken as prescribed by the doctor. Like all medicines, Panect DSR may cause side effects, although not everybody gets them. The most common side effects of Panect DSR are diarrhoea, stomach pain, flatulence (gas), dryness in the mouth, dizziness, and headache. Everyone doesn’t need to experience the above side effects. In case of any discomfort, speak with your doctor.
It is recommended not to use if you are allergic to any ingredinets present in it. Prolonged intake of Pantoprazole is associated with a low level of Vitamin B12 and low magnesium. Hence yearly test of Vitamin B12 and magnesium is required if you are taking Panect DSR for the long term. Use of Panect DSR is contraindicated in people with lupus (autoimmune inflammatory disease). Try to avoid caffeine-containing beverages (coffee, tea), spicy/deep fried/processed foods, carbonated drinks, acidic foods like citrus fruits/vegetables (tomatoes).
Uses of Panect DSR
Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of food pipe (esophagitis), Peptic ulcer.
Medicinal Benefits
Panect DSR plays a vital role in preventing nausea, vomiting, stomach upset, stomach pain, peptic ulcer, and other conditions due to hyperacidity or acid reflux. Pantoprazole prevents the proton pumps gate from producing an excessive amount of stomach acid. While Domperidone stops nausea (feeling sick) and vomiting (being sick) blocking messages between parts of your brain called the chemoreceptor trigger zone (CTZ) and the vomiting centre.
Directions for Use
Swallow it as a whole with water; do not crush, break or chew it.
Warning and Precautions
Drug Warnings
You should avoid taking Panect DSR if you are allergic to Panect DSR or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Panect DSR may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Panect DSR may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Panect DSR may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor.
Drug Interactions
Drug-Drug Interactions: Panect DSR may interact with a blood thinner (e.g. clopidogrel, warfarin), antifungal (e.g. ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (e.g. atazanavir, nelfinavir), iron supplements, antibiotic (e.g. ampicillin, rifampicin), heart medicine (e.g. digoxin) and anti-cancer drug (e.g. methotrexate). Let your doctor know if you are taking these medicines.
Drug-Food Interactions: Panect DSR interact with St John’s wort plant that is used as an anti-depressant. This plant may affect the working of Panect DSR. So avoid its intake with Panect DSR.
Drug-Disease Interactions: Panect DSR should be not given in patients with C. difficile induced colitis, liver disease, bone fractures, low Vitamin B12 (anaemia), low magnesium (hypomagnesemia).
- It is best to avoid alcohol while taking medication.
- If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. You should use this medicine only if your doctor considers the benefit for you greater than the potential risk for your unborn child or baby.
- Panect DSR should be used in breastfeeding mothers only if the benefits outweigh the risks.
- Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking Panect DSR you should not drive or operate any machinery or vehicles.
- In patients with severe liver impairment, the liver enzymes should be monitored regularly during treatment with pantoprazole, particularly on long-term use
- Inform your doctor before receiving the Panect DSR if you have a kidney impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.
- Panect DSR can be given safely to children provided; dose has been prescribed by a child specialist.
FAQ
How does Panect DSR work?
Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and in this way reduces the feeling of bloating, or fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone – CTZ) located in your brain, which is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum.
How long can I take Panect DSR?
Panect DSR can be safely taken as long as your doctor has prescribed it to you.
Can Panect DSR cause brittle bones?
Yes, taking Panect DSR for a very long time can cause calcium depletion from the body leading to weakening of bones. Hence a calcium and vitamin D supplement is recommended along with Panect DSR to replenish calcium depletion in the body.
Does Panect DSR interfere or affect laboratory test reports?
Yes. Panect DSR can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.
How can I manage my long term side effects?
Prolonged intake of Panect DSR may weaken your bone and lower haemoglobin level. Your doctor may prescribe you Vitamin B12 for enhancing haemoglobin and calcium/vitamin D/magnesium supplements for bone health.
Can I take Pantoprazole and Domperidone together?
Combination of pantoprazole and domperidone is effective & safe.
Can I take Panect DSR on my own for acidity?
No, Panect DSR is a prescribed drug with minimal side effects. Only take it if your doctor has recommended it to you for acidity.
